CYCLONITE (RDX) | Occupational Safety and Health Administration

CYCLONITE (RDX)†

Chemical Identification
CAS #	121-82-4
Formula	C₃H₆N₆O₆
Synonyms	cyclotrimethylene trinitramine, (desensitized); cyclotrimethylenetrinitramine; hexahydro-1,3,5-trinitro-s-triazine; RDX; trimethylenetrinitramine; 1,3,5-trinitro-1,3,5-triazacyclohexane

Physical Properties
Physical description	White, crystalline powder.
Boiling point		Molecular weight	222.2
Freezing point/melting point	401°F	Vapor pressure	0.0004 mmHg at 230°F
Flash point	explodes	Vapor density
Specific gravity	1.82	Ionization potential
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating		NFPA fire rating
NFPA reactivity rating		NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	2224
Sampling group
Sampler/Sampling media	GFF (37 mm), Type A/E [AP4003705]
Sampling time^*
Sampling volume (TWA)^*	120 L
Sampling flow rate (TWA)^*	1 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	HPLC-UV
Method reference	OSHA PV2135 (partially validated)
Notes
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method	Limit the amount of bulk submitted to 1 g or 1 mL.

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA	1.5 mg/m³ (Construction and Maritime only)	REL-TWA	1.5 mg/m³	TLV-TWA	0.5 mg/m³ [1994]	PEL-TWA	0.07 mg/m³
PEL-STEL		REL-STEL	3 mg/m³	TLV-STEL		PEL-STEL
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	Y	Skin notation	Y	Skin notation	Y	Skin notation	Y
Notes: The OSHA PEL applies to Construction and Maritime Industries only. See 29 CFR 1926.55 Table 1 and 29 CFR 1915.1000 Table Z-Shipyards		Notes:		Notes:		Notes:
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications: TLV-A4, EPA-C		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Cyclotrimethylene trinitramine, [desensitized]

NIOSH: Pocket Guide to Chemical Hazards - Cyclonite

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Cyclonite. See annual publication for most recent information.
U.S. EPA Integrated Risk Information System: Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) (CASRN 121-82-4).
Goldberg, D.J., Green, S.T., Nathwani, D., McMenamin, J., Hamlet, N. and Kennedy, D.H.: RDX intoxication causing seizures and a widespread petechial rash mimicking meningococcaemia. J. R. Soc. Med. 85(3): 181, 1992.
Küçükardali, Y., et al.: Accidental oral poisoning caused by RDX (cyclonite): a report of 5 cases. J. Intensive Care Med. 18(1): 42-46, 2003.
Pohanish, R.P. (editor): Cyclonite. Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 731-732.

Last Updated Date : 06/06/2022

CYCLONITE (RDX)†

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References