METHYLENEDIANILINE (4-4'-METHYLENEDIANILINE; MDA)‡
| CAS # | 101-77-9 |
|---|---|
| Formula |
C₁₃H₁₄N₂ |
| Synonyms |
4,4'-diaminodiphenylmethane; para, para'-diaminodiphenyl-methane; dianilinomethane; 4,4'-diphenylmethanediamine |
| Physical description | Pale-brown, crystalline solid with a faint, amine-like odor. | ||
|---|---|---|---|
| Boiling point | 748°F | Molecular weight | 198.3 |
| Freezing point/melting point | 198°F | Vapor pressure | 0.0000002 mmHg at 77°F |
| Flash point | 430°F | Vapor density | 6.8 |
| Specific gravity | 1.15 | Ionization potential | 10.70 eV |
| Lower explosive limit (LEL) | Upper explosive limit (UEL) | ||
| NFPA health rating | 2 | NFPA fire rating | 1 |
| NFPA reactivity rating | 0 | NFPA special instruction | |
| Vapor hazard ratio (VHR) | |||
| Historical exceedance percentage | |||
| Target organs | |||
| Analyte code (IMIS no.) | 1732 | ||
|---|---|---|---|
| Sampling group | |||
| Sampler/Sampling media | 2 GFFs (37 mm) coated with sulfuric acid, in 3-piece cassette, separated by the ring section [SKC 225-9004] | ||
| Sampling time* | 100 min |
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| Sampling volume (TWA)* |
100 L |
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| Sampling flow rate (TWA)* |
1 L/min |
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| Sampling volume (STEL/Peak/C)* |
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| Sampling flow rate (STEL/Peak/C)* |
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| Analytical method instruments | GC-ECD | ||
| Method reference | OSHA 57 (fully validated) | ||
| Notes |
Within 10 hours after sampling, transfer filters to glass vial containing 2 mL deionized water. |
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| Special requirements |
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* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.
| Wipe Sampler/Sampling media |
Wipe with GFFs wetted with 0.6 mL of a 60/40 methanol/deionized water solution. Wipe samples are placed in a solution of 0.07 N H₂SO₄ for shipment. Solutions of 60/40 methanol/deionized water and 0.07 N H₂SO₄ are available from the SLTC for OSHA staff. Kits for on-site screening of aromatic amines are available from commercial suppliers. [AP4003705] |
|---|---|
| Bulk Method |
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| Device | |||||
|---|---|---|---|---|---|
| Model/Type | |||||
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Sampling information (see manufacturer instructions) |
|
OSHA PEL
8-hour TWA (ST) STEL (C) Ceiling Peak |
NIOSH REL
Up to 10-hour TWA (ST) STEL (C) Ceiling |
ACGIH TLV©
8-hour TWA (ST) STEL (C) Ceiling |
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|---|---|---|---|---|---|---|---|
| PEL-TWA |
10 ppb [5 ppb Action Level] |
REL-TWA |
|
TLV-TWA |
0.1 ppm [1992] |
PEL-TWA |
0.01 ppm (0.08 mg/m³) |
| PEL-STEL |
100 ppb |
REL-STEL |
|
TLV-STEL |
|
PEL-STEL |
0.1 ppm (0.8 mg/m³) |
| PEL-C |
|
REL-C |
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TLV-C |
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PEL-C |
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| Skin notation |
N |
Skin notation |
N |
Skin notation |
Y |
Skin notation |
Y |
| Notes: |
Notes:
CARCINOGEN (Ca); REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION (LOQ 0.03 mg/m³). See Appendix A, NIOSH Potential Occupational Carcinogens. |
Notes:
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Notes:
See also California Code of Regulations, Title 8 §1535. Methylenedianiline. (Construction) and §5200. Methylenedianiline. (General Industry) |
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| Health factors: See NIH-NLM PubChem. | IDLH | ||||||
| Carcinogenic classifications: IARC-2B, NIOSH-Ca, NTP-R, OSHA-Ca, TLV-A3 |
Notes:
Ca |
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AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
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Additional Resources and Literature References
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NOAA: CAMEO Chemicals - 4,4'-Diaminodiphenylmethane NIOSH: Pocket Guide to Chemical Hazards - 4,4'-Methylenedianiline Literature References
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Last Updated Date : 01/05/2021