ISOPHORONE DIISOCYANATE

Chemical Identification

CAS # 4098-71-9
Formula

C₁₂H₁₈N₂O₂

Synonyms

IPDI, isocyanic acid, methylene (3,5,5-trimethyl-3,1-cyclohexylene) ester, 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl-isocyanate, isophorone diamine diisocyanate

Physical Properties

Physical description Colorless to slightly yellow liquid with a pungent odor.
Boiling point Molecular weight 222.3
Freezing point/melting point -76°F Vapor pressure 0.0003 mmHg
Flash point 311°F Vapor density
Specific gravity 1.06 Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating 2 NFPA fire rating 1
NFPA reactivity rating 1 NFPA special instruction W: Reacts violently or explosively with water.
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA

Analyte code (IMIS no.) 1539
Sampling group
Sampler/Sampling media Isocyanate Sampling Filter Kit - GFF (37 mm, open-faced) coated with 1 mg 1-(2-pyridyl)piperazine [SLTC103]
Sampling time*

15 min

Sampling volume (TWA)*

15 L

Sampling flow rate (TWA)*

1 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments UHPLC
Method reference OSHA 5002 (fully validated)
Notes

Refrigerate coated filters until used. Sample open-faced!!

Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method

Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques

Device
Model/Type
Sampling information
(see manufacturer instructions)

Exposure Limits

OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA REL-TWA

0.005 ppm (0.045 mg/m³)

TLV-TWA

0.005 ppm [1985]

PEL-TWA

0.005 ppm (0.045 mg/m³)

PEL-STEL REL-STEL

0.02 ppm (0.180 mg/m³)

TLV-STEL PEL-STEL

0.02 ppm

PEL-C REL-C TLV-C PEL-C
Skin notation

N

Skin notation

Y

Skin notation

N

Skin notation

Y

Notes:

Not established

Notes: Notes: Notes:
Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: Not listed Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

Last Updated Date : 04/14/2021