AMITROLE

Chemical Identification
CAS #	61-82-5
Formula	C₂H₄N₄
Synonyms	aminotriazole; 3-aminotriazole; 2-amino-1,3,4-triazole; 3-amino-1,2,4-triazole

Physical Properties
Physical description	Colorless to white, crystalline powder.
Boiling point		Molecular weight	84.1
Freezing point/melting point	318°F	Vapor pressure	<0.000008 mmHg
Flash point		Vapor density
Specific gravity	1.14	Ionization potential
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating	1	NFPA fire rating	1
NFPA reactivity rating	0	NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	A176
Sampling group
Sampler/Sampling media	Midget fritted glass bubbler (MFGB) containing 10 mL Distilled Water [Infrequently Requested Method - OSHA staff please contact SLTC before sampling 801-233-5100]
Sampling time^*
Sampling volume (TWA)^*	60 L
Sampling flow rate (TWA)^*	1 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	HPLC-UV
Method reference	OSHA PV2006 (partially validated)
Notes
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA	0.2 mg/m³	TLV-TWA	0.2 mg/m³ [1983]	PEL-TWA	0.2 mg/m³
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	NA	Skin notation	N	Skin notation	N	Skin notation	N
Notes: Not established		Notes: CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION. See Appendix A, NIOSH Potential Occupational Carcinogens.		Notes:		Notes:
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications: IARC-3, NIOSH-Ca, NTP-R, TLV-A3		Notes: Ca
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Amitrole

NIOSH: Pocket Guide to Chemical Hazards - Amitrole

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Amitrole. See annual publication for most recent information.
Environmental Protection Agency: R.E.D. Facts: Amitrole. Publication No. EPA-738-F-96-002 (August) 1996, 13 pp.
Hurley, P.M.: Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents. Environ. Health Perspect. 106(8): 437-445, 1998.
Pohanish, R.P. (editor): 3-Amino-1,2,4-Triazole. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 143-144.
Putnam, C.D., Arvai, A.S., Bourne, Y. and Tainer, J.A.: Active and inhibited human catalase structures: ligand and NADPH binding and catalytic mechanism. J. Mol. Biol. 296(1): 295-309, 2000.

Last Updated Date : 01/22/2024

AMITROLE

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References