ACETONITRILE†
| CAS # | 75-05-8 |
|---|---|
| Formula |
CH₃CN |
| Synonyms |
cyanomethane; ethyl nitrile; methyl cyanide; ACN |
| Physical description | Colorless liquid with an aromatic odor. | ||
|---|---|---|---|
| Boiling point | 179°F | Molecular weight | 41.1 |
| Freezing point/melting point | -49°F | Vapor pressure | 73 mmHg |
| Flash point | 42°F (open cup) | Vapor density | 1.42 |
| Specific gravity | 0.787 | Ionization potential | 12.20 eV |
| Lower explosive limit (LEL) | 3.0% | Upper explosive limit (UEL) | 16% |
| NFPA health rating | 2 | NFPA fire rating | 3 |
| NFPA reactivity rating | 0 | NFPA special instruction | |
| Vapor hazard ratio (VHR) | |||
| Historical exceedance percentage | |||
| Target organs | |||
| Analyte code (IMIS no.) | 0060 | ||
|---|---|---|---|
| Sampling group | |||
| Sampler/Sampling media | CSC tube (400/200 mg) [SKC 226-09] | ||
| Sampling time* | |||
| Sampling volume (TWA)* | 1-25 L |
||
| Sampling flow rate (TWA)* | 0.01-0.2 L/min |
||
| Sampling volume (STEL/Peak/C)* | |||
| Sampling flow rate (STEL/Peak/C)* | |||
| Analytical method instruments | GC-FID | ||
| Method reference | NIOSH 1606 (fully validated) | ||
| Notes | Keep samples refrigerated when not in transit. Ship samples overnight with cold-packs as soon as possible. |
||
| Special requirements |
* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.
| Wipe Sampler/Sampling media | |
|---|---|
| Bulk Method |
| Device | |||||
|---|---|---|---|---|---|
| Model/Type | |||||
|
Sampling information (see manufacturer instructions) |
|
OSHA PEL
8-hour TWA (ST) STEL (C) Ceiling Peak |
NIOSH REL
Up to 10-hour TWA (ST) STEL (C) Ceiling |
ACGIH TLV©
8-hour TWA (ST) STEL (C) Ceiling |
|||||
|---|---|---|---|---|---|---|---|
| PEL-TWA |
40 ppm (70 mg/m³) |
REL-TWA |
20 ppm (34 mg/m³) |
TLV-TWA | PEL-TWA |
40 ppm (70 mg/m³) |
|
| PEL-STEL | REL-STEL | TLV-STEL | PEL-STEL |
60 ppm (105 mg/m³) |
|||
| PEL-C | REL-C | TLV-C | PEL-C | ||||
| Skin notation |
N |
Skin notation |
N |
Skin notation |
Y |
Skin notation |
Y |
| Notes: | Notes: |
Notes:
Visit the ACGIH TLV site for specific data |
Notes: | ||||
| Health factors: See NIH-NLM PubChem. | IDLH |
500 ppm |
|||||
| Carcinogenic classifications: TLV-A4, EPA-CBD; D | Notes: | ||||||
| AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3: | |||||||
Additional Resources and Literature References
|
NOAA: CAMEO Chemicals - Acetonitrile NIOSH: Pocket Guide to Chemical Hazards - Acetonitrile Literature References
|
Last Updated Date : 03/25/2024