Label abbreviations descriptions

DIMETHYL SULFATE†

Chemical Identification
CAS # 77-78-1
Formula

C₂H₆O₄S
Synonyms

dimethyl ester of sulfuric acid; dimethylsulfate; methyl sulfate

Physical Properties
Physical description Colorless, oily liquid with a faint, onion-like odor.
Boiling point 370°F (decomposes) Molecular weight 126.1
Freezing point/melting point -25°F Vapor pressure 0.1 mmHg
Flash point 182°F Vapor density
Specific gravity 1.33 Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating 4 NFPA fire rating 2
NFPA reactivity rating 1 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 0960
Sampling group
Sampler/Sampling media Porapak Q tube (150/75 mg) [SKC 226-115]
Sampling time*
Sampling volume (TWA)*

10 L
Sampling flow rate (TWA)*

0.1 L/min
Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FPD
Method reference OSHA PV2147 (partially validated)
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device Detector tube
Model/Type Dräger - Dimethyl Sulfate 0.005/c, 6718701
Sampling information
(see manufacturer instructions) 		200 strokes, 0.005-0.05 ppm range, uncertainty approx 50%

Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA

1 ppm (5 mg/m³)

 REL-TWA

0.1 ppm (0.5 mg/m³)

 TLV-TWA

0.1 ppm [1985]

 PEL-TWA

0.1 ppm (0.5 mg/m³)
PEL-STEL REL-STEL TLV-STEL PEL-STEL
PEL-C REL-C TLV-C PEL-C
Skin notation

Y

 Skin notation

Y

 Skin notation

Y

 Skin notation

Y
Notes:

See 29 CFR 1910.1000 Table Z-1.

 Notes:

CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION. See Appendix A

 Notes: Notes:
Health factors:  See NIH-NLM PubChem. IDLH

 7 ppm
Carcinogenic classifications: IARC-2A, NOSH-Ca, NTP-R, TLV-A3, EPA-B2 Notes:

Ca
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

Last Updated Date : 12/28/2020