METHYL VINYL KETONE

Chemical Identification
CAS #	78-94-4
Formula	C₄H₆O
Synonyms	3-butene-2-one; acetyl ethylene; butenone; MVK; methylene acetone

Physical Properties
Physical description	A clear colorless liquid with a pungent odor.
Boiling point	179°F	Molecular weight	70.1
Freezing point/melting point	20°F	Vapor pressure	86 mmHg at 72°F
Flash point	20°F	Vapor density	2.41
Specific gravity	0.8407	Ionization potential
Lower explosive limit (LEL)	2.1%	Upper explosive limit (UEL)	15.6%
NFPA health rating	4	NFPA fire rating	3
NFPA reactivity rating	2	NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)
Sampling group
Sampler/Sampling media
Sampling time^*
Sampling volume (TWA)^*
Sampling flow rate (TWA)^*
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments
Method reference
Notes
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA		TLV-TWA		PEL-TWA
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C		REL-C		TLV-C	0.001 ppm [2018]	PEL-C	0.05 ppm (0.14 mg/m³)
Skin notation	NA	Skin notation	NA	Skin notation	N	Skin notation	Y
Notes: Not established		Notes: Not established		Notes:		Notes:
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications: Not listed		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Methyl vinyl ketone

NIOSH: Pocket Guide to Chemical Hazards - Methyl vinyl ketone

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Dimethyl sulfate. See annual publication for most recent information.
EPA Air Toxics Website: Dimethyl sulfate. U.S. Environmental Protection Agency Technology Transfer Network.
Dimethyl sulfate. IARC Monogr. Eval. Carcinog. Risks Hum. 71(Pt. 2): 575-588, 1999.
Pohanish, R.P. (editor): Dimethyl Sulfate. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 939-941.
Schettgen, T., Broding, H.C., Angerer, J. and Drexler, H.: Dimethyl sulphate: a hidden problem in occupational medicine. Occup. Environ. Med. 61(1): 73-75, 2004.
Wang, Y., Xia, J. and Wang, Q.: Clinical report on 62 cases of acute dimethyl sulfate intoxication. Am. J. Ind. Med. 13(4): 455-462, 1988.

Last Updated Date : 01/05/2021

METHYL VINYL KETONE

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References