DIETHYL PHTHALATE

Chemical Identification
CAS #	84-66-2
Formula	C₁₂H₁₄O₄
Synonyms	DEP; diethyl ester of phthalic acid; ethyl phthalate

Physical Properties
Physical description	Colorless to water-white, oily liquid with a very slight, aromatic odor.
Boiling point	563°F	Molecular weight	222.3
Freezing point/melting point	-41°F	Vapor pressure	0.002 mmHg at 77°F
Flash point	284°F	Vapor density	7.66
Specific gravity	1.12	Ionization potential
Lower explosive limit (LEL)	0.7% at 367°F	Upper explosive limit (UEL)	0.75 at 368°F
NFPA health rating	1	NFPA fire rating	1
NFPA reactivity rating	0	NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	0933
Sampling group
Sampler/Sampling media	OSHA versatile sampler (OVS-Tenax®) - 13 mm Tenax® tube (140/70 mg) with GFF enclosed [SKC 226-56]
Sampling time^*
Sampling volume (TWA)^*	240 L
Sampling flow rate (TWA)^*	1 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	GC-FID
Method reference	OSHA 104 (fully validated)
Notes
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA	5 mg/m³	TLV-TWA	5 mg/m³ [1996]	PEL-TWA	5 mg/m³
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	NA	Skin notation	N	Skin notation	N	Skin notation	N
Notes: Not established		Notes:		Notes:		Notes:
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications: TLV-A4, EPA-D		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Diethyl phthalate

NIOSH: Pocket Guide to Chemical Hazards - Diethyl phthalate

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Diethyl phthalate. See annual publication for most recent information.
U.S. EPA Integrated Risk Information System: Diethyl phthalate (CASRN 84-66-2).
Api, A.M.: Toxicological profile of diethyl phthalate: a vehicle for fragrance and cosmetic ingredients. Food Chem. Toxicol. 39(2): 97-108, 2001.
Blount, B.C., et al.: Levels of seven urinary phthalate metabolites in a human reference population. Environ. Health Perspect. 108(10): 979-982, 2000.
David, R.M., Lockhart, L.K. and Ruble, K.L.: Lack of sensitization for trimellitate, phthalate, terephthlate and isobutyrate plasticizers in a human repeated insult patch test. Food Chem. Toxicol. 41(4): 589-593, 2003.
Pohanish, R.P. (editor): Diethyl Phthalate. In, Sittig’s Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 880-882.
Scott, R.C., Dugard, P.H., Ramsey, J.D. and Rhodes, C.: In vitro absorption of some o-phthalate diesters through human and rat skin. Environ. Health Perspect. 74: 223-227, 1987.

Last Updated Date : 01/29/2021

DIETHYL PHTHALATE

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References