1-METHOXY-2-PROPANOL

Chemical Identification
CAS #	107-98-2
Formula	C₄H₁₀O₂
Synonyms	Dowtherm209®; 1-methoxy-2-hydroxypropane; 1-methoxy-2-propanol; 2-methoxy-1-methylethanol; propylene glycol methyl ether

Physical Properties
Physical description	Clear, colorless liquid with a mild, ethereal odor.
Boiling point	248°F	Molecular weight	90.1
Freezing point/melting point	-139°F (sets to glass)	Vapor pressure	12 mmHg
Flash point	97°F	Vapor density	3.11
Specific gravity	0.96	Ionization potential
Lower explosive limit (LEL)	1.6%	Upper explosive limit (UEL)	13.8%
NFPA health rating	1	NFPA fire rating	3
NFPA reactivity rating	0	NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	2210
Sampling group
Sampler/Sampling media	CSC tube (100/50 mg) [SKC 226-01]
Sampling time^*	100 min
Sampling volume (TWA)^*	10 L
Sampling flow rate (TWA)^*	0.1 L/min
Sampling volume (STEL/Peak/C)^*	3 L
Sampling flow rate (STEL/Peak/C)^*	0.2 L/min
Analytical method instruments	GC-FID
Method reference	OSHA 99 (fully validated)
Notes
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA	100 ppm (360 mg/m³)	TLV-TWA	50 ppm [2012]	PEL-TWA	100 ppm (360 mg/m³)
PEL-STEL		REL-STEL	150 ppm (540 mg/m³)	TLV-STEL	100 ppm [2012]	PEL-STEL	150 ppm (540 mg/m³)
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	NA	Skin notation	N	Skin notation	N	Skin notation	Y
Notes: Not established		Notes:		Notes:		Notes:
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications: TLV-A4		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - 1-Methoxy-2-propanol

NIOSH: Pocket Guide to Chemical Hazards - Propylene glycol monomethyl ether

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - 1-Methoxy-2-propanol. See annual publication for most recent information.
EPA Integrated Risk Information System: Propylene glycol monomethyl ether (PGME) (CASRN 107-98-2).
Devanthéry, A., Berode, M. and Droz, P.O.: Propylene glycol monomethyl ether occupational exposure. 3. Exposure of human volunteers. Int. Arch. Occup. Environ. Health 75(4): 203-208, 2002.
Emmen, H.H., Muijser, H., Arts, J.H. and Prinsen, M.K.: Human volunteer study with PGME: eye irritation during vapor exposure. Toxicol. Lett. 140-141: 249-259, 2003.
Pohanish, R.P. (editor): Propylene Glycol Monomethyl Ether. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1974-1976.
Wilkinson, S.C. and Williams, F.M.: Effects of experimental conditions on absorption of glycol ethers through human skin in vitro. Int. Arch. Occup. Environ. Health 75(8): 519-527, 2002.

Last Updated Date : 09/22/2022

1-METHOXY-2-PROPANOL

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References