ACETOPHENONE

Chemical Identification
CAS #	98-86-2
Formula	C₈H₈O
Synonyms	α-acetophenone; acetylbenzene; 1-phenylethanone; phenyl methyl ketone

Physical Properties
Physical description	A colorless liquid with a sweet pungent taste and odor resembling the odor of oranges.
Boiling point	395.1°F	Molecular weight	120.16
Freezing point/melting point	67.5°F	Vapor pressure
Flash point	180°F	Vapor density
Specific gravity	1.028	Ionization potential
Lower explosive limit (LEL)	1.1%	Upper explosive limit (UEL)	6.7%
NFPA health rating	2	NFPA fire rating	2
NFPA reactivity rating	0	NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	A169
Sampling group
Sampler/Sampling media	Tenax® GC tube (30/15 mg) [SKC 226-35]
Sampling time^*	120 min
Sampling volume (TWA)^*	12 L
Sampling flow rate (TWA)^*	0.1 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	GC-FID
Method reference	OSHA PV2003 (partially validated)
Notes
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media
Bulk Method

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA		TLV-TWA	10 ppm [2008]	PEL-TWA	10 ppm (49 mg/m³)
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	NA	Skin notation	NA	Skin notation	N	Skin notation	N
Notes: Not established		Notes: Not established		Notes:		Notes:
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications: EPA-D		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Acetophenone

NIOSH: Pocket Guide to Chemical Hazards - Acetophenone

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Acetophenone. See annual publication for most recent information.
NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: AM5250000.
International Chemical Safety Cards (WHO/IPCS/ILO): Acetophenone.
U.S. EPA Integrated Risk Information System: Acetophenone (CASRN 98-86-2).
Eberde, E.G. (editor) Drugs and chemicals general price list. The Southern Pharmaceutical Journal 5(4): 1-7, 1912.
Pohanish, R.P. (editor) Acetophenone. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 44-45.

Last Updated Date : 12/15/2020

ACETOPHENONE

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References