VANADIUM, RESPIRABLE DUST & FUME (as V₂O₅) | Occupational Safety and Health Administration

VANADIUM, RESPIRABLE DUST & FUME (as V₂O₅)†

Chemical Identification
CAS #	1314-62-1
Formula	V₂O₅
Synonyms	vanadium pentoxide fume, divanadium pentoxide fume, vanadic anhydride fume, vanadium oxide fume, vanadium pentoxide dust; other synonyms vary depending on the specific vanadium compound

Physical Properties
Physical description	Yellow-orange powder or dark-gray, odorless flakes dispersed in air.
Boiling point	3182°F (decomposes)	Molecular weight	181.9
Freezing point/melting point	1274°F	Vapor pressure	0 mmHg (approx)
Flash point		Vapor density
Specific gravity	3.36	Ionization potential
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating		NFPA fire rating
NFPA reactivity rating		NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	2571	2571 (fume); request analyte codes 9135 & 2571	2570 (resp dust); request analyte codes 9130 & 2570
Sampling group	METALSSG-2
Sampler/Sampling media	Pre-assembled cassette with mixed cellulose ester filter (MCEF) 0.8 micron (25 or 37 mm) [MAWP025A0 or MAWP037A0]	Tared low-ash 37 mm PVC filter, 5 microns [SLTC108]	Tared low-ash 37 mm PVC filter, 5 microns, preceded by 10 mm nylon Dorr-Oliver cyclone for respirable samples. [SLTC108]
Sampling time^*	240-480 min	240-480 min	240-480 min
Sampling volume (TWA)^*	480-960 L	960 L	816 L
Sampling flow rate (TWA)^*	2 L/min	2 L/min	1.7 L/min ±5%
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	ICP	Gravimetric	Gravimetric
Method reference	OSHA ID-125G (fully validated)	OSHA PV2121 (partially validated)	OSHA PV2121 (partially validated)
Notes	Results will be reported from the elemental analysis for the element only; the stated identity of the actual sample contents is based on the assumption that the material sampled is as identified by the compliance officer using available documentation of materials and processes. An elemental result provided may be converted to the desired compound by multiplying the result by the appropriate stoichiometric factor. A 91B report specific to the compound (including the stoichiometric conversion) may by be provided upon request by contacting the laboratory. The stoichiometric factor for vanadium pentoxide (V₂O₅) from vanadium is 1.785. The physical form of a sample (dust, mist, or fume) is identified by the compliance officer using available documentation of materials and processes. Smaller filters recommended for sampling inside welding hoods.	Results will be reported from the elemental analysis for the element only; the stated identity of the actual sample contents is based on the assumption that the material sampled is as identified by the compliance officer using available documentation of materials and processes. An elemental result provided may be converted to the desired compound by multiplying the result by the appropriate stoichiometric factor. A 91B report specific to the compound (including the stoichiometric conversion) may by be provided upon request by contacting the laboratory. The stoichiometric factor for vanadium pentoxide (V₂O₅) from vanadium is 1.785. The physical form of a sample (dust, mist, or fume) is identified by the compliance officer using available documentation of materials and processes.	Results will be reported from the elemental analysis for the element only; the stated identity of the actual sample contents is based on the assumption that the material sampled is as identified by the compliance officer using available documentation of materials and processes. An elemental result provided may be converted to the desired compound by multiplying the result by the appropriate stoichiometric factor. A 91B report specific to the compound (including the stoichiometric conversion) may by be provided upon request by contacting the laboratory. The stoichiometric factor for vanadium pentoxide (V₂O₅) from vanadium is 1.785. The standard applies to the Respirable Fraction.
Special requirements	For the entire suite of analytes listed in METALSSG-2, request analyte code 2587.	FOR TOTAL DUST SAMPLES, DO NOT USE A CYCLONE!!	Samples must be collected with a Dorr-Oliver cyclone.

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media	Ghost Wipe [SKC 225-2414]
Bulk Method	This analysis is for the metal component of this analyte only. The conversion back to the analyte is a mathematical one assuming all metal present is from the analyte source. Request using analyte code V125.

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA		TLV-TWA	0.05 mg/m³ (inhalable particulate matter) [2008]	PEL-TWA	0.05 mg/m³
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C	0.1 mg/m³ (fume); 0.5 mg/m³ (respirable dust)	REL-C	0.05 mg/m³ [15 minutes]	TLV-C		PEL-C
Skin notation	N	Skin notation	N	Skin notation	N	Skin notation	N
Notes: See 29 CFR 1910.1000 Table Z-1.		Notes: The REL applies to all vanadium compounds except vanadium metal and vanadium carbide.		Notes:		Notes: See footnote (n).
Health factors: See NIH-NLM PubChem.		IDLH	35 mg/m³ (as V)
Carcinogenic classifications: TLV-A3, IARC-2B		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Vanadium (fume or dust)

NIOSH: Pocket Guide to Chemical Hazards - Vanadium fume

Literature References

NOAA: CAMEO Chemicals - Vanadium pentoxide.
NIOSH: Pocket Guide to Chemical Hazards - "a href="https://www.cdc.gov/niosh/npg/npgd0653.html" title="Vanadium dust">Vanadium dust.
ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Vanadium pentoxide [1314-62-1], as V. See annual publication for most recent information.
ATSDR: Toxicological Profile for Vanadium. 2009.
Barceloux, D.G.: Vanadium. J. Toxicol. Clin. Toxicol. 37(2): 265-278, 1999.
Ehrlich, VA et al.: Inhalative exposure to vanadium pentoxide causes DNA damage in workers; results of a multiple end point study. Environ Health Perspect. 116(12): 1689-1693, 2008.
Heinemann, G., Fichtl, B. and Vogt, W.: Pharmacokinetics of vanadium in humans after intravenous administration of a vanadium containing albumin solution. Br. J. Clin. Pharmacol. 55(3): 241-245, 2003.
Irsigler, G.E., Visser, P.J. and Spangenberg, P.A.L.: Asthma and chemical bronchitis in vanadium plant workers. Am. J. Ind. Med. 35(4): 366-374, 1999.
NIOSH: Occupational Health Guideline for Vanadium Pentoxide Fume. 1978.
NIOSH/IPCS: International Chemical Safety Cards - Vanadium Pentoxide. 2006.
Ress, N.B. et al.: Carcinogenicity of inhaled vanadium pentoxide in F344/N rats and B6C3F1 mice. Toxicol. Sci. 74(2): 287-296, 2003.
Rondini, EA., Walters, DM., and Bauer, AK.: Vanadium pentoxide induces pulmonary inflammation and tumor promotion in a strain-dependent manner. Part Fibre Toxicol. 12: 7-9, 2010.

Last Updated Date : 06/14/2023

Group Sampling Information
Sampling Media	Sampling Time (If there are exceptions they will be in Notes)	TWA Sampling Volume (If there are exceptions they will be in Notes)	TWA Flow Rate (If there are exceptions they will be in Notes)
mixed cellulose ester filter (MCEF)	240-480 min	480-960 L	2 L/min

Analytes Sampling Information
Analytes	IMIS Code	Wipe Sampling	Incompatibilities
Iron*	I200	Yes, with a Ghost Wipe
Vanadium*	V125	Yes, with a Ghost Wipe
Zinc*	Z100	Yes, with a Ghost Wipe
Chromium, Metal & Insoluble salts (as Cr)**	0685	Yes, with a Ghost Wipe	Hexavalent Chromium
Cobalt, Metal, Dust & Fume (as Co)	0720	Yes, with a Ghost Wipe	Tungsten
Copper Dust & Mists (as Cu)	0730	Yes, with a Ghost Wipe
Copper Fume (as Cu)	0731	Yes, with a Ghost Wipe
Iron Oxide Fume	1520	Yes, with a Ghost Wipe
Manganese, Compounds & Fume (as Mn)***	1620	Yes, with a Ghost Wipe
Molybdenum, Dust & Insoluble compounds, (as Mo)	1790	Yes, with a Ghost Wipe
Nickel, Metal, & Insoluble compounds (as Ni)	1840	Yes, with a Ghost Wipe
Vanadium, Respirable Dust & Fume	2571	Yes, with a Ghost Wipe
Zinc Oxide Fume	2610	Contact SLTC for information

Notes

Request any or all of these analytes together. Entire group can be requested with analyte code 2587.

Results for unrequested analytes in this group will be reported if significant amount are found.

There is no need to contact SLTC before sampling.

This analysis can be pre-analyzed gravimetrically if collected on a pre-weighted PVC filter obtained from SLTC.

*These 3 codes are used for bulk sample results in place of their metal oxides.

**Please note that this is NOT hexavalent chromium.

***For Manganese STEL take only a 10-30 L sample.

VANADIUM, RESPIRABLE DUST & FUME (as V₂O₅)†

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References